Han Peng's direct corner goal in the 47th minute and Temwa Chawinga's goal in the 81st minute helped Wuhan secure a 4-0 victory, despite a missed penalty by Beatriz Zaneratto Joao in the 78th minute.
The result has increased the pressure on Athletic Bilbao coach Gaizka Garitano, whose post-match comments that "the Primera Liga is difficult for us" was criticized by the fans.
Julian Draxler, Idrissa Gueye and Kylian Mbappe added another three in the second half while Angers pulled one back in the 52nd minute.
Lenglet's suspension means he misses the game against his former club and highlights the lack of options at the back, where youngster Ronald Araujo is the only alternative to partner Gerard Pique in the heart of the Barca back four.
Third seed Elina Svitolina cruised past 27th-seeded Ekaterina Alexandrova 6-4, 7-5 to advance to the next round. Argentinian qualifier Nadia Podoroska extended her stunning run on clay after the restart of the season, as the 23-year-old dispatched Anna Karolina Schmiedlova 6-3, 6-2 to become the first Argentinian women's player to reach the fourth round in Paris since 2011. Enditem
The Rams, as the champions of the previous three seasons are nicknamed, started off well and dominated 4-1 after the first half of the game, led by the Canadian forward Matthew Mistele's two goals, but the visitors from Michalovce produced a miraculous comeback by scoring four in a row.
As for player updates, Germany's Han Ying enters the action at the Women's World Cup in place of Australia's Melissa Tapper, and Germany's Patrick Franziska replaces Australia's Hu Heming to participate in the Men's World Cup. Enditem
"I need to shoulder more responsibilities," said Guo, who joined Hebei during the offseason.
Mainz were unable to gain a foothold into the first half and had to wait until the 38th minute to get their first chance on target, as Jean-Philippe Mateta's header came close.
Shanxi took over early in the second quarter, constantly attacking the basket through Fu and Liu in the paint, but Hebei soon charged back with a 9-0 run. Shanxi piled up a 43-38 lead at the break.
Shanxi and Henan played out a close game, although Shanxi ultimately won 76-70. Shanxi led the game by 9 points after the first half, but Henan did very well to surpass Shanxi in the third quarter.